Zebrafish Embryos Immune System induction with BSA as an initial Screening model for Covid-19 Treatment

نویسندگان

چکیده

The early phase of embryonic development involves a lot signaling and growth factor proteins that will influence the interactions among cells. Administration BSA (Bovine Serum Albumin) at beginning embryo can interferes organogenesis causing abnormalities in development. Administrations were expected to induce responses immune system, which be hoped mimicking stress on system caused by infection such as covid-19. This study aimed screen right dose zebrafish model animal further for covid-19 treatment. research was conducted Laboratory Animal Histology Embryology, Faculty Biology, Universitas Gadjah Mada. Eggs immersed 1%, 2.5% 5% imemersed 1 hours 5 repeated 3 times. Parameter survivalability rate, morphology, physiological performance contraction muscle per minutes also heart rate minutes. data obtained tested ANOVA DMRT test with confidence level 95%. result showed 1% has significant effect normal organ function embryos, conclusion is most effective

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ژورنال

عنوان ژورنال: IOP conference series

سال: 2021

ISSN: ['1757-899X', '1757-8981']

DOI: https://doi.org/10.1088/1755-1315/755/1/012012